支气管哮喘血清ECP检测的临床应用

目的:检测血清ECP含量并探讨其在支气管哮喘患者中的临床应用价值。方法:使用UniCAPl00型自动酶免疫荧光分析系统测定。结果:正常人ECP含量为(4.76±3.28)μg/L;38例支气管哮喘患者急性发作期:治疗前ECP含量为(23.75±32.50)μg/L,治疗后ECP含量为(8.36±5.27)μg/L,41例缓解期支气管哮喘患者ECP含量为(10.98±4.24)μg/L。哮喘患者急性发作期,缓解期血清ECP水平均高于正常人,统计学差异有显著性(P<0.01)。结论:血清ECP水平反映气道的炎症程度,并可作为哮喘的诊断,疗效监测和预后判断指标。

Clinical Application of Astnma Patients Examined ECP

Objective To determine the serum ECP level and evaluate its clinical application in the asthma patients.Methods The serum ECP concentrations were measured by UniCAP automatic enzyme-fluoroimmunoassay system.Results The serum ECP concentrations of normal subjects was(4.76±3.28)μg/L of 38 asthmatic patients with acute asthma before the treatment was(23.75±32.50)μg/L;And after the treatments was(8.36±5.27)μg/L;The serum ECP concentrations of 41 asthmatic patients in remission was(10.98±4.24)μg/L.The serum level of ECP in the patients with acute asthma and in remission were higher than that of normal subjects.And it showed difference(P<0.01).Conclusion The serum ECP level reflects airway inflammatory status and helps predict the exacerbation and severity of asthma.It might be a useful marker in diagnosis of asthma and in monitoring the efficacy Of anti-inflammatory treatment in asthma.