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Disseminated intravascular coagulation due to IgM-mediated autoimmune hemolytic anemia |
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| Authors: | Bleakly N Teresa Fontaine Magali J Pate Lisa L Sutherland Scott M Jeng Michael |
| Affiliation: | Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California, USA. |
| Abstract: | Disseminated intravascular coagulation (DIC) due to red cell hemolysis has been previously attributed to transfusion-related hemolytic reactions, but not to autoimmune hemolytic anemia. We report a case of DIC in a child with complement-fixing IgM-mediated cold-agglutinin autoimmune hemolysis, which resulted in arterial thrombosis and gangrene of the upper and lower extremities. |
| Keywords: | autoimmune hemolytic anemia cold agglutinin syndrome disseminated intravascular coagulation |
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