Antidiuretic-hormone-induced morphological changes in the ampullary epithelium of the frog semicircular canal |
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Authors: | O. Oudar E. Ferrary G. Feldmann |
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Affiliation: | (1) Département de Physiologie, UNSERM U.251, Paris, France;(2) INSERM U. 327 Laboratoire de Biologie cellulaire Faculté de Médecine Xavier Bichat, Université Paris 7, Paris, France;(3) Faculté de Médecine Xavier Bichat, Laboratoire de Biologie cellulaire, 16 rue Henri Huchard, F75018 Paris, France |
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Abstract: | Summary Morphological changes induced by in vitro treatment with arginine-vasotocin, the frog antidiuretic hormone, were studied in the ampullary epithelium of the frog semicircular canal. Morphological changes appeared only in the apical side of the dark cells, while the basal part of these cells and the other cells lining the semicircular canal did not show any change. Changes consisted of the appearance of numerous small vesicles in the apical cytoplasm and the development of microvilli on the apical plasma membrane of the dark cells. These results suggest that arginine-vasotocin could play a role in the regulation of endolymph section. |
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Keywords: | Arginine-vasotocin Dark cell-Frog Vestibular ultrastructure |
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