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肺结核空洞住院患者结核菌耐药性分析
引用本文:邵旭光,吴琦,孙昕,李莉. 肺结核空洞住院患者结核菌耐药性分析[J]. 吉林医学, 2012, 0(34): 7474-7475
作者姓名:邵旭光  吴琦  孙昕  李莉
作者单位:天津市呼吸疾病研究所天津市海河医院呼吸内科;天津医科大学总医院呼吸内科;天津市海河医院呼吸内科
摘    要:目的:探讨肺结核空洞住院患者结核菌耐药性特征。方法:采用BACTEC MGIT快速培养仪做痰结核菌耐药性及药敏试验。结果:肺结核空洞患者总耐药率,耐单药率,耐多药率高于肺结核未出现空洞患者;耐药顺序从高到低依次为:异烟肼(H)、链霉素(S)、利福平(R)、乙胺丁醇(E)。结论:高耐药率,尤其是肺结核空洞患者高耐药率,应引起全社会的重视,寻找一条切实可行的控制耐药结核菌的办法是目前的当务之急。

关 键 词:肺结核  空洞  耐药性

Analysb of the tuberculosis drug-resistance characteristics of pulmonary tuberculosis with cavitary of hospitalized patients
Affiliation:SHAO Xu-guang1,WU Qi2,SUN Xin1,et al.(1.Department of Respiratory Disease,Tianjin Haihe Hospital,Tianjin Institute of Respiratory Disease,Tianjin 300350,China;2.Department of Respratory,General Hospital of Tianjin Medicine Hospital Tianjin 300053 China)
Abstract:Objective To investigate the tuberculosis drug-resistance characteristics of tuberculosis with cavitary of hospitalized patients in our city.Method We used rapid culture system with BACTEC MGIT to do sputum drug resistance and sensitivity test.Results(1)The total resistance rate,single drug resistance rate and emergence of MDR-TB rates were higher in patients with pulmonary tuberculosis cavity than in patients without cavity;(2) resistance order from high to low was:H,S,R,E.Conclusion High resistance rates of drug resistance tuberculosis,especially in patients with pulmonary tuberculosis cavity,should be payed a attention by the whole society.Looking for a practical way to control drug-resistant tuberculosis is a current priority.
Keywords:Pulmonary tuberculosis  Cavitary  Drug resistance
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