重型颅脑损伤并发急性肾功能衰竭危险因素分析

目的 探讨重型颅脑损伤患者并发急性肾功能衰竭的危险因素.方法 收集812例重型颅脑损伤患者相关临床资料,设立ARF组,采用x2检验,进行统计学处理.结果 812例患者中有56例并发ARF,ARF组与非ARF死亡率分别为33.93%、20.11%,两组间有非常显著性差异.统计结果显示,年龄、伤情、低血容量、高血浆渗透压,多脏器功能损害与ARF的发生显著相关.结论 ARF进一步增加了重型颅脑损伤患者的死亡率,高龄、低GCS评分、低血容量、高血浆渗透压、上消化道出血并肺部感染是ARF发生的危险因素.

Analysis on the risk factors in patients with severe brain injury accompanied by acute renal failure(ARF)

Objective To investigate the risk factors in patients with severe brain injury accompanied by acute renal failure(ARF).Methods Relative clinical information gathered from 812 cases of severe brain injury,which were divided into ARF group and non-ARF group,and processed by statistical: x2 test.Results In a total of 812 cases,acute renal failure occurred in 56 patients.The marked difference was found between ARF group whose fatality rate was 33.93% and non-ARF group whose fatality rate was 20.11%.Statistics identified the following factors: age;trauma;hypovolemia;plasma hyperosmolarity and severe brain injury,which were related with ARF obviously.Conclusions ARF further increased the fatality rate of severe brain injury and the risk factor of ARF is higher age,lower Glasgow coma scale,hypovolemia,plasma hyperosmolarity and upper gastrointestinal bleeding with complicated pulmonary infection.