l-DOPA improves odor discrimination learning in rats |
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Authors: | Pavlis Michelle Feretti Casara Levy Alan Gupta Nita Linster Christiane |
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Affiliation: | Department of Neurobiology and Behavior Mudd Hall, Cornell University, Ithaca, NY 14853, USA. |
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Abstract: | Using a forced-choice odor discrimination task in rats, we show here that intraperitoneal injections of l-DOPA improve rats' odor discrimination performance in comparison to control rats injected with saline. Although the exact mechanism of l-DOPA and potential action on dopamine receptors remains unclear, the present results indicate that rats injected with the 20-50 mg/kg of l-DOPA performed significantly better in an odor discrimination task than did control rats. In addition, we observed a significant correlation between the concentration of l-DOPA and odor discrimination performance. |
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Keywords: | smallcaps" >l-DOPA Olfaction Rats Discrimination |
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