婴幼儿皮肤念珠菌病与缺铁性贫血相关性探讨

目的探讨婴幼儿皮肤念珠菌病与缺铁性贫血的相关性,以及补铁治疗在婴幼儿皮肤念珠菌病中的作用。方法回顾性分析101例婴幼儿皮肤念珠菌病患儿的临床资料,筛查出60例缺铁性贫血患儿,并将其随机分为观察组和对照组各30例,所有患儿均给予营养治疗和外用氟康唑粉扑治疗,观察组在此基础上口服右旋糖苷铁分散片,30d后比较疗效。结果经治疗后,观察组缺铁性贫血治疗有效率为90.00%(27/30),明显高于对照组的66.67%(20/30),差异具有统计学意义(P<0.05);观察组皮肤念珠菌病治疗有效率为96.67%(29/30),明显高于对照组的80.00%(24/30),差异具有统计学意义(P<0.05)。结论缺铁性贫血可能是婴幼儿皮肤念珠菌病的一个重要诱因,而补铁治疗可增加患儿机体抵抗力,提高治疗效果。

Correlation analysis on cutaneous candidiasis and iron deficiency anemia in infants

Objective To investigate the correlation of cutaneous candidiasis and iron deficiency anemia in infants, and explore the effects of iron supplement in cutaneous candidiasis. Methods We retrospectively analyzed the clinical data of 101 infants with cutaneous candidiasis, and screened 60 children with iron deficiency anemia, which were randomly divided into the study group and the control group, each with 30 cases. Patients in the study group were given nutritional therapy and treated with fluconazole, while those in the study group were given oral ferrous fumarate particles on this basis of the control group. Thirty days after treatment, the clinical effects were compared. Results After treatment, the effective rate of iron deficiency anemia in the study group was 90.00% (27/30), significantly higher than that in the control group [66.67% (20/30)], P<0.05. The effective rate of cutaneous candidiasis in the study group was 96.67% (29/30), significantly higher than that in the control group [80.00% (24/30)], P<0.05. Conclusion The iron deficiency anemia may be an important incentive in cutaneous candidiasis of infants, while iron supplement can increase the resistance in children and improve the therapeutic effect.