高血糖对COPD急性加重期患者预后的影响

目的探讨高血糖对慢性阻塞性肺病(COPD)急性加重期预后的影响。方法收集2009年1月至2010年2月于我院住院治疗的COPD急性加重期患者75例,根据患者入院时空腹血糖或随机血糖测定结果 ,分成高血糖组42例,血糖正常组33例,比较两组患者一般临床资料、住院期间的并发症发生和病死情况。结果高血糖组中高血脂、PaCO2<60mmHg及PaCO2>50mmHg的病例数明显多于血糖正常组(P<0.05)。高血糖组患者肺心病、呼吸衰竭、肾功能不全、肺功能异常及心力衰竭的发生率均明显高于血糖正常组(P<0.05),住院天数明显长于血糖正常组(P<0.05),住院期间病死率也明显高于血糖正常组(P<0.05)。结论高血糖对AECOPD患者的预后存在明显的不利影响。

Influence of hyperglycemia on the prognosis of patients with acute exacerbation of chronic obstructive pulmonary disease

Objective To observe the influence of hyperglycemia on the prognosis of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods Seventy-five AECOPD patients in our hospital from January 2009 to December 2010 were divided into the high blood glucose group (n=42) and the normal blood glucose group (n=33) based on the admission glucose. The clinical data, the incidence of complication and the prognosis were compared between the two groups. Results The patients with high blood cholesterol, PaCO2<60 mmHg and PaCO2>50 mmHg in the high blood glucose group were more than that in the normal blood glucose group (P<0.05). The incidence of pulmonary heart disease, respiratory failure, renal insufficiency, craniocerebral injury and heart failure in the high blood glucose group were higher than those in the normal blood glucose group (P<0.05). The length of stay in the high blood glucose group was longer than that in the normal blood glucose group (P<0.05). The mortality rate in the high blood glucose group was higher than that in the normal blood glucose group (P<0.05). Conclusion Hyperglycemia might be associated with the prognosis of patients with AECOPD.