输精管结扎后家兔血清及精浆的前列腺酸性磷酸酶活力变化 |
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引用本文: | Wang Yan,Liang Shuyuan ,Liu Xichun,et al.输精管结扎后家兔血清及精浆的前列腺酸性磷酸酶活力变化[J].吉林大学学报(医学版),1997(1). |
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作者姓名: | Wang Yan Liang Shuyuan Liu Xichun |
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作者单位: | Dept.of Productive Pathophysiology,Center of Laboratory,The 3rd Clinical College |
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摘 要: | 成年日本大耳白雄兔42只,随机分为输精管结扎25月组(VG25)14只和假手术25月组(SOG25)11只;输精管结扎6月组(VG6)9只和假手术6月组(SOG6)8只。均于体重2.5~3.0kg(5月龄)时行输精管结扎或假手术。在相同条件下检测前列腺酸性磷酸酶(PAP)的活力。结果表明:①血清PAP活力,有随增龄增高的趋势,输精管结扎对该酶活性无影响(P>0.05)。②精浆PAP活力:VG6明显低于SOG6(P<0.01);VG25也明显低于SOG25(P<0.01)。提示输精管结扎无提高前列腺癌标志酶—PAP活性的作用;精浆中的PAP除主要来自前列腺之外,另有一部分可能来自睾丸。
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关 键 词: | 输精管结扎 前列腺 家兔 酸性磷酸酶 |
Activity changes of prostatic acid phosphatase in serum and seminal plasma of rabbits vasectomized |
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Abstract: | Japanese white male rabbits were randomly divided into four groups: vasectomized 6-month and 25-month groups (VG6,VG25),Sham operated 6-month and 25-month groups (SOG6, SOG25).On te same condition,activities of prostatic acid phosphatase (PAP) were determined.The results showed:(1)There were a tendency towards increase of PAP activities in serum and vasectomy didn′t affect the activties. ( P >0 05).(2) Activities of PAP in seminal plasma were obviously lower in VG6 and VG25 than those in SDG6 and SOG25 respectively ( P <0.01).The results indicated that vasectomy could not increase activity of PAP,an index of proxtatic cancer;PAP might also be secreted by testis besides prostate. |
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Keywords: | Vasctomy Prostate Rabbit Acid Phosphatase |
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