Binding of botulinum neurotoxin to the synaptosome fraction of rat brain |
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| Authors: | Masaru Kitamura |
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| Affiliation: | (1) The 2nd Department of Bacteriology, National Institute of Health, 141 Shinagawa-ku, Tokyl, Japan |
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| Abstract: | Summary The radioactive 125I-labelled neurotoxin of C. botulinum type A, when incubated with rat brain homogenate, is bound selectively to the synaptosome fraction. Intact toxin was liberated from the synaptosome fraction by treatment with Triton X-100, SDS, trypsin or neuraminidase. |
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| Keywords: | Botulinum neurotoxin Synaptosome Rat brain |
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