心血管支架与支架置入后的血管快速内皮化

血管支架已被广泛应用于临床治疗心血管疾病,但由此产生的并发症也日益显露出来，支架置入后血管内皮化是影响支架材料与人体生物相容性的关键因素。支架置入后血管内皮功能异常，引发内皮层剥脱，导致血小板聚集、炎症反应、血管平滑肌细胞增殖迁移、细胞外基质形成等一系列病理反应，造成支架内再狭窄，因此促进血管内皮细胞损伤、修复及功能改变在支架内再狭窄中起着重要作用。为了进一步了解所选用的支架置入人体后如何发生快速的血管内皮化反应及寻找如何解决支架置入后血管内皮化的途径，文章通过检索大量文献，来对支架置入后的快速血管内皮化进行探讨分析，以寻求较好的解决途径。

Intravascular stent and rapid vascular endothelialization following stent implantation

Intravascular stent has been widely used in clinic to treat cardiovascular diseases, but the complications gradually present. Vascular endothelialization following stent implantation is a key factor that influences the biocompatibility of material and human body. After stent implantation, vascular endothelium function is abnormal, inducing endodermis shedding, platelet aggregation, inflammatory reactions, vascular smooth muscle cell proliferation and migration, and excellular matrix formation. These pathological reactions cause in-stent restenosis. So repair and functional changes of vascular endothelial cells play an important role in in-stent restenosis. To deeply understand the vascular endothelialization following implantation of various stents, this paper discussed rapid vascular endothelialization by retrieving articles so as to search a method to solve this problem.