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A complex translocation in a 5-year-old boy with acute myeloblastic leukemia |
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| Authors: | J Harbott R Engel B Rudolph F Lampert |
| Abstract: | A complex translocation [t(2;10;11)(q34;q11;q13)], an extra chromosome #8, and a duplication of 17q were the major findings in blast cells found in the bone marrow of a 5-yr-old boy with AML-M2 both before treatment and during relapse. The child died 8.5 mo after diagnosis, despite intensive combination chemotherapy. |
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