Epidemiology of recurrences or reinfections of Clostridium difficile-associated diarrhea |
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Authors: | Barbut F Richard A Hamadi K Chomette V Burghoffer B Petit J C |
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Affiliation: | Department of Microbiology, H?pital Saint-Antoine, Assistance Publique-H?pitaux de Paris, Paris, France. frederic.barbut@sat.ap-hop-paris.fr |
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Abstract: | Approximately 15 to 35% of patients with a first episode of Clostridium difficile-associated diarrhea relapse within 2 months. Between 1994 and 1997, strains from 93 hospitalized patients with C. difficile recurrences were fingerprinted by using both serotyping and PCR-ribotyping. The results showed that 48.4% of clinical recurrences were, in fact, reinfections with a different strain of C. difficile. Rates of clinical recurrences could therefore be reduced by implementing strict isolation precautions. |
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