动态血压监测评估高血压子代亲属血压水平的意义

目的 通过动态血压监测结果分析原发性高血压患者的子代亲属与非高血压子代亲属间的差异,并评估高血压子代亲属中原发性高血压患者服药后血压控制效果.方法 （1）对原发性高血压子代亲属72例（检测组）和非高血压子代亲属61例（对照组）分别进行动态血压监测,比较24h血压平均值、血压负荷值、血压变异性（BPV）.（2）对确诊为原发性高血压的高血压子代亲属患者,经药物治疗8周后行动态血压监测,评价药物治疗疗效.结果 （1）检测组BPV、血压负荷值均高于对照组,差异有统计学意义（P均＜0.05）,24 h血压平均值两组间差异无统计学意义.（2）经药物治疗后,检测组中原发性高血压患者的24 h血压平均值较用药前差异具有统计学意义（P均＜0.05）,7例收缩压谷峰比值（T/P）大于50％,6例舒张压T/P大于50％;6例收缩压及舒张压平滑指数（SI）大于1,3例收缩压及舒张压SI小于1.结论 （1）动态血压监测能对原发性高血压子代亲属血压状态做出早期评价,对该组高血压正常高值患者和高血压患者早期预防或控制血压有一定意义.（2）动态血压监测较好的评价原发性高血压子代亲属中高血压患者血压控制效果,帮助患者选择最佳药物和最佳用药方式平稳降压.

Significance of ambulatory blood pressure monitoring in the evaluation of blood pressure level in offspring of patients with hypertension

Objective To analyze the differences between the offspring of patients with essential hypertension and those of non-hypertensive patients by ambulatory blood pressure monitoring results,and to assess blood pressure control results in offspring of patients with essential hypertension after taking medication.Methods （1） Ambulatory blood pressure monitoring was performed in 72 offspring of patients with essential hypertension （the study group）and 61 offspring of non-hypertensive patients （the control group）.Comparison was made between the two groups in 24-hour average blood pressure,blood pressure load,blood pressure variability （BPV）.（2） For offspring diagnosed with essential hypertension,the efficacy was evaluated by ambulatory blood pressure monitoring after eight weeks of drug treatment.Results （1） In the study group,blood pressure load values were significantly higher than those in the control group （P＜0.05）.No significant difference was found in 24-hour average blood pressure between the two groups.（2） After drug treatment,the patients with essential hypertension and 24-hour average blood pressure in the study group showed statistically significant difference with those before treatment （P＜0 05）.The systolic blood pressure T/P was larger than 50％ in 7 cases,and diastolic blood pressure T/P was greater than 50％ in 6 cases.The systolic and diastolic blood pressure SI was larger than 1 in 6 cases,and lower than 1 in 3 cases.Conclusion （1） Ambulatory blood pressure monitoring would make an early assessment of offspring with essential hypertension by blood pressure status.There are great significances for early prevention or blood pressure control to the hypertensive group of normal patients and patients with hypertension.（2） Ambulatory blood pressure monitoring is a good evaluation for the results of blood pressure control in offspring of patients with hypertension,which helps patients choose the best drugs and the best medication.