肥胖型支气管哮喘患者合并阻塞性睡眠呼吸暂停综合征临床分析

目的本研究初步探讨了肥胖型支气管哮喘患者合并阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的临床特点。方法评价95例诊断为肥胖型支气管哮喘患者的年龄、性别、睡眠打鼾史、高血压史、吸烟史、饮酒史、动脉血压。使用多导睡眠监测系统记录睡眠过程中的多次生理事件,评价AHI和最低血氧饱和度(SaO_2),使用哮喘控制测试问卷(ACT)评估哮喘控制情况。结果肥胖型支气管哮喘患者48.4%合并有阻塞性睡眠呼吸暂停,肥胖型支气管哮喘合并阻塞性睡眠呼吸暂停组与单纯哮喘组对比,肺通气功能更差、哮喘控制率更低。结论肥胖型支气管哮喘患者易合并阻塞性睡眠呼吸暂停,导致哮喘不易控制。

Clinical analysis of obese bronchial asthma patients with obstructive sleep apnea syndrome

Objective To investigate the clinical features of obese bronchial asthma patients with obstructive sleep apnea syndrome. Methods Their age, gender, blood pressure, and history of sleep symptoms, hypertension, smoking and alcohol consumption of 95 obese patients with bronchial asthma were recorded. All patients underwent polysomnography. Apnea-hypopnea index ( AHI) and lowest O2 ( SaO2 ) saturation were calculated. ACT score was used to assess the control of asthma. Results 48. 4% of obese patients with bronchial asthma were diagnosed with obstructive sleep apnea. Patients with OSAHS and asthma showed worse lung function and low asthma control rate compared with that without OSAHS. Conclusion High prevalence of obstructive sleep apnea is observed in obese patients with bronchial asthma, which Results in therapy failure.