常频机械通气和鼻塞式持续气道正压通气在新生儿呼吸衰竭的疗效对比

目的比较常频机械通气(CMV)与鼻塞式持续气道正压通气(NCPAP)治疗新生儿呼吸衰竭的临床疗效及并发症情况。方法回顾性分析2012年1月至2014年12月该院新生儿科收治的125例呼吸衰竭并应用NCPAP及CMV治疗的新生患儿,比较治疗后两组患儿的治疗效果、血气分析、生命体征及并发症情况。结果 NCPAP组有效率为84.5%,CMV组有效率为79.6%,两组之间比较差异无统计学意义(P0.05)。通气治疗后两组患儿血气分析、生命体征均逐渐恢复正常并维持平稳,各项指标均得到明显改善。NCPAP组治疗过程中出现的并发症发生率为8.5%%,明显低于CMV组并发症的发生率(31.5%)(P0.05)。结论 NCPAP治疗新生儿呼吸衰竭疗效与常频机械通气差异不大,但具有无创、操作简易的优势,是临床治疗新生儿呼吸衰竭的一种较为理想通气模式。

Comparison of clinical curative effect between CMV and NCPAP in the treatment of neonatal respiratory failure

Objective To compare the clinical curative effect and complications between CMV and NCPAP in the treatment of neonatal respiratory failure. Methods The medical data of 125 patients with neonatal respiratory failure, who were given NCPAP and CMV from January 2012 to December 2014, were retrospectively analyzed to compare their curative effect, the indexes of blood gas and vital signs, and complications. Results The effective rate after treatment in the NCPAP group was 84. 5%, and 79. 6% in the CMV group (P>0. 05). The blood gas and vital signs in the two groups after ventilation treatment were restored to normal gradually and maintained stable, and all the indexes were obviously improved. The incidence of complications in the NCPAP therapy group was 8. 5%, which was significantly lower than that in the CMV group (31. 5%) (P<0. 05). Conclusion The curative effect in the NC-PAP ventilation treatment of neonatal respiratory failure is similar with the CMV treatment. The NCPAP is an ideal ventilation mode in the clinical treatment of neonatal respiratory failure, with the advantages of non-invasive and easy operation.