红细胞分布宽度与简化肺栓塞严重指数关系的临床研究

目的通过探讨红细胞分布宽度(RDW)与简化肺栓塞严重指数(s PESI)的关系来预测急性肺栓塞危险程度。方法将90例急性肺栓塞患者分为s PESI低危组和高危组,比较两组患者在基本资料、血常规、凝血功能、肝肾功能、胸部影像学及心脏彩超等方面的差异。结果 s PESI高危组与低危组比较,在心率、收缩压、凝血酶原时间、国际标准化比值、中性粒细胞、RDW、累及主肺动脉及右心室增大等方面,差异有统计学意义(P0.05);logistic单因素回归分析发现收缩压、INR、RDW、累及主肺动脉、右心室增大与s PESI分组有关(P0.05);logistic多因素回归分析发现累及主肺动脉是影响s PESI分组的独立危险因素(P0.05)。结论 RDW在s PESI高危组与低危组差异有显著性,但不是预测s PESI分组的独立危险因素,对急性肺栓塞危险程度的判断有一定价值。

Clinical study of relationship between red blood distribution width and simplified pulmonary embolism sever-ity index

Objective To explore the relationship between red blood distribution width ( RDW) and simpli-fied pulmonary embolism severity index (sPESI) for predicting the severity of acute pulmonary embolism .Methods 90 cases of acute pulmonary embolism were divided into the sPESI low risk group and the high risk group , then their basic information, blood routine, liver function, renal function, chest imaging and echocardiography were com-pared.Results The difference was statistically significant between the high risk group and the low risk group in heart rate, systolic blood pressure, prothrombin time (PT), international normalized ratio (INR), the neutral granu-lar cells, RDW, main pulmonary artery involvement and right ventricle enlargement (P<0.05).Univariate logistic regression analysis showed sPESI grouping was associated with systolic blood pressure , INR, RDW, main pulmonary artery involvement and right ventricle enlargement ( P<0.05 ) .Multivariate logistic regression analysis showed that main pulmonary artery involvement was the independent risk factor for predicting sPESI grouping of acute pulmonary embolism (P<0.05).Conclusion The difference is statistically significant for RDW between the sPESI high risk group and the low risk group , while it is not an independent risk factor for predicting sPESI grouping .RDW has a certain value in judging the risk degree of acute pulmonary embolism .