肺康复对稳定期慢性阻塞性肺疾病的疗效分析

目的探讨肺康复锻炼对稳定期慢性阻塞性肺疾病患者的临床疗效及意义。方法 300例稳定期慢阻肺患者,采用前瞻性随机对照法分为两组:康复组(n=149)给予门诊慢阻肺健康宣教,包括饮食干预,戒烟教育,用药指导;肺康复锻炼(呼吸运动训练联合步行运动训练)。对照组(n=151)仅给予门诊慢阻肺健康宣教。比较6个月后两组患者的血气分析、肺功能、6MWD(6分钟步行距离)及慢阻肺急性加重期住院的次数等。结果 6个月后共234例完成试验,康复组(n=121)较对照组(n=113)的6MWD,血气分析等指标有明显改善,具有统计学意义(P0.05),而两组间肺功能FEV_1/FVC、FEV_1%和慢阻肺急性加重期住院的次数无统计差异(P0.05)。结论肺康复锻炼(呼吸运动训练联合步行运动训练)能有效提高PaO_2及降低PaCO_2,提高6MWD,适度改善运动耐力,是一种简便易行的康复锻炼方法,值得临床应用及推广。

Clinical research of pulmonary rehabilitation exercise on patients with stable chronic obstructive pulmonary disease

Objective To evaluate the treatment significance and influence of pulmonary rehabilitation exer-cise on patients with stable COPD. Methods A total of 300 stable COPD patients were randomly divided into two groups. The rehabilitation group ( n=149 ) was given pulmonary rehabilitation guidance, including diet, smoking cessation education, medication guidance, pulmonary rehabilitation exercise ( respiratory exercise combined with walk exercise training). The control group (n=151) was given COPD health education, including diet, smoking cessation education, medication guidance without exercise training. Blood gas analysis, pulmonary function, 6 minutes walking distance and readmission rate of AECOPD were measured in all patients before and after treatment. Results 6 month after the treatment, 234 stable COPD patients completed test. 6MWD and blood gas analysis improved more signifi-cantly in the rehabilitation group than in the control group ( P<0. 05 ) , but there was no significant difference in FEV1/FVC, FEV1% and readmission rate of AECOPD between the two groups (P>0. 05). Conclusion Pulmona-ry rehabilitation exercise ( respiratory exercise combined with walk exercise training) can effectively improve the level of PaO2 and reduce PaCO2 , improve exercise tolerance, and enhanced 6MWD, which is a simple and convenient ex-ercise and worthy of clinical application and promotion.