椎体骨髓状况的磁共振波谱评估

目的 探讨椎体氢质子磁共振波谱对椎体骨髓状况的评估价值. 方法 对152例(30～80岁,平均58岁±14岁)女性志愿者进行腰椎MR检查.首先常规扫描矢状位T_2WI、T_1WI和横轴位T_2WI.MR常规扫描结束后采用单体素PRESS序列对L_2～L_4椎体进行波谱采集,相应谱线采用SAGE 7.0软件分析并计算相关椎体MRS定量指标.结果 随年龄增大椎体脂肪含量(FF%)逐步增加;椎体水峰线宽(LW)随年龄增加呈逐渐变窄趋势;椎体脂峰线宽未见明显变化趋势.结论氢质子磁共振波谱可以在常规腰椎磁共振基础上无创性地评估椎体骨髓变化状况.

MR Spectroscopy in Evaluating the Bone Marrow of Vertebra

Objective To assess the value of MRS in evaluating vertebral bone marrow. Methods A total of 152 female volunteers (mean age 58±14 years, ranged 30～80 years) were recruited in this study. All subjects underwent vertebral MRS examination after routine MRI examination (sagittal T_2WI, T_1WI and axial T_2WI). Single voxel (SV) was chosen for the 1H MRS acquisition at L_2～L_4 vertebral body with PRESS sequence. MRS parameters were measured by SAGE 7.0 software. Results The fat fraction (FF%) of vertebra ascend with aging;the water line width (LW) decrease with aging and there was not obvious tendency with lipid LW. Conclusion Vertebral MRS can be considered as a noninvasive examination added to routine spine MRI to demonstrate the changes of vertebral bone marrow.