NMDA receptor antagonist MK-801 infused into the insular cortex prevents the attenuation of gustatory neophobia in rats |
| |
| Authors: | Figueroa-Guzmán Yazmín Kuo Jeffrey S Reilly Steve |
| |
| Affiliation: | Department of Psychology, University of Illinois at Chicago, 1007 West Harrison Street, Chicago, IL 60607, USA. yazminfg@uic.edu |
| |
| Abstract: | Gustatory neophobia dissipates with repeated exposures to an initially novel taste solution. The aim of the present study was to determine whether NMDA receptors in the insular cortex are involved in this experience-dependent process. Results showed that acute microinfusion of MK-801 into the insular cortex prevented the attenuation of gustatory neophobia indicating that this process is an NMDA receptor-dependent phenomenon. |
| |
| Keywords: | Gustatory neophobia MK-801 Insular cortex NMDA receptor Rat |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
