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阿昔洛韦与盐酸左旋氧氟沙星注射液配伍稳定性的试验研究
引用本文:刘雪丽,王晓璐. 阿昔洛韦与盐酸左旋氧氟沙星注射液配伍稳定性的试验研究[J]. 齐鲁药事, 2006, 25(2): 109-110
作者姓名:刘雪丽  王晓璐
作者单位:青岛市中心医院,青岛,266042
摘    要:目的在室温下考察阿昔洛韦与盐酸左旋氧氟沙星注射液配伍稳定性。方法采用分光光度法测定配伍液中阿昔洛韦及盐酸左旋氧氟沙星的含量变化,并在200~400nm进行紫外扫描,同时观察外观及pH值变化。结果配伍液尽管在8h内pH值、吸收峰峰形及峰位无明显变化,但颜色、含量及吸收峰峰值有变化。结论临床应用时,二者需分开输注,不宜混合配伍应用。

关 键 词:阿昔洛韦  左旋氧氟沙星  配伍稳定性
文章编号:1672-7738(2006)02-0109-02

Study on the stability of aciclovir and levofloxacin injection mixture
LIU Xue-li,WANG Xiao-lu. Study on the stability of aciclovir and levofloxacin injection mixture[J]. qilu pharmaceutical affairs, 2006, 25(2): 109-110
Authors:LIU Xue-li  WANG Xiao-lu
Abstract:OBJECTIVE To observe the changes of stability of aciclovir and levofloxacin injection mixture at 25℃ METHODS The UV spectrophotometry was used to observe the changes of contents and absorption curves of the mixture in different time.The pH and appearance of mixture were also observed.RESULTS The contents and appearance of mixture had changed in room temperature within 8 hours.CONCLUSION Acyclovir and levofloxacin injection can not be mixed to use.
Keywords:Aciclovir  levofloxacin injection  intermixture stability
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