| 车祸应激患者血清NO、SOD测定及人格特征的相关研究 |
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| 引用本文： | 刘光雄,杨来启,许向东,王晓峰,张宏斌,张彦,马文涛,吴兴曲,王蓉蓉.车祸应激患者血清NO、SOD测定及人格特征的相关研究[J].中国临床心理学杂志,2002,10(3):218-219. |
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| 作者姓名： | 刘光雄 杨来启 许向东 王晓峰 张宏斌 张彦 马文涛 吴兴曲 王蓉蓉 |
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| 作者单位： | 解放军第三医院精神科,陕西宝鸡,721004 |
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| 摘 要： | 许多资料表明 ,强烈应激或长期应激状态损害健康 ,甚至造成组织损伤 ,引发疾病。强烈的精神刺激引起的急性应激障碍和创伤后应激障碍 (ＰＴＳＤ) ,可表现出记忆、学习等认知障碍及行为障碍 ,氧自由基对脑细胞毒性作用可能参与发病1] 。研究表明 ,氧自由基是一类高毒性化合物 ,能作用于中枢神经组织中的糖蛋白及氨基酸 ,导致蛋白质变性 ,细胞膜失去稳定甚至细胞死亡1] 。本文以车祸为应激源进行研究 ,探讨应激对患者血清ＮＯ水平和ＳＯＤ活性的影响 ,并结合人格特征进行了分析。1 对象和方法1.1 研究对象研究组为 1999年 8月至 2 0 0 0年…
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| 关 键 词： | 车祸 应激 一氧化氮 超氧化物歧化酶 创伤后应激障碍 发病机制 |
| 文章编号： | 1005-3611(2002)03-0218-02 |
| 修稿时间： | 2001年8月30日 |
Serum NO Level and SOD Activity in Patients with Traffic Accident |
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| LIU Guang-xiong,YANG Lai-qi,XU Xiang-dong,et al.Serum NO Level and SOD Activity in Patients with Traffic Accident[J].Chinese Journal of Clinical Psychology,2002,10(3):218-219. |
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| Authors: | LIU Guang-xiong YANG Lai-qi XU Xiang-dong |
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| Institution: | LIU Guang-xiong,YANG Lai-qi,XU Xiang-dong,et al Department of sychiatry,The Third Hospital of PLA,Baoji 721004,China |
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| Abstract: | Objective: To explore the stress effects of traffic accident on changing the NO level and SOD activity, as well as the relationship between personality and prognostic change. Methods: Serum level of NO and activity of SOD were measured in 152 patients with traffic accidents and in 60 control subjects. All subjects were assessed with the Eysenck Personality Questionnaire (EPQ). Results: NO and SOD were significantly higher in patients as compared to controls ( P <0.01). Correlation analysis showed that SOD score negatively correlated with N score of EPQ ( P <0.05), and NO score positively correlated with N and P scores of EPQ ( P <0.05).Conclusion: Healthy personality may play an important role to enhance the ability to cope with stress. |
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| Keywords: | Traffic accident Stress NO SOD Personality |
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