Value of skin tests for the choice of a neuromuscular blocking agent after an anaphylactic reaction |
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| Authors: | Dewachter P Mouton-Faivre C Pertek J-P Boudaa C Mertes P-M |
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| Affiliation: | 1. Department of Anesthesiology, Zhejiang Provincial People''s Hospital, People''s Hospital of Hangzhou Medical College, 158 Shangtang Road, Hangzhou 310014, Zhejiang Province, China;2. Department of Orthopedics, Zhejiang Provincial People''s Hospital, People''s Hospital of Hangzhou Medical College, 158 Shangtang Road, Hangzhou 310014, Zhejiang Province, China;3. Department of Pharmacy, Hangzhou Third Hospital, 38 West Lake Avenue, Hangzhou 310009, Zhejiang Province, China |
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| Abstract: | We report a grade III allergic hypersensitivity reaction occurring in a 72-year-old patient immediately after anaesthesia induction. Anaphylaxis to cisatracurium was diagnosed on clinical symptoms, biological tests and positivity of the cutaneous tests to this neuromuscular blocking agent. Five days after this allergological assessment, rocuronium, a muscle relaxant for which skin tests appeared negative was used during surgery without adverse effects. The authors underline the value of a detailed allergological assessment to identify the pathophysiologic mechanism, the culprit drug and to propose a safer alternate drug that might be used. |
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