Effects on bone mineral density of calcium and vitamin D supplementation in elderly women with vitamin D deficiency |
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| Authors: | Grados Franck Brazier Michel Kamel Saïd Duver Sigolène Heurtebize Nathalie Maamer Mohamed Mathieu Marc Garabédian Michèle Sebert Jean-Luc Fardellone Patrice |
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| Institution: | Rheumatology Department, North Hospital Group, 80054 cedex 1, Amiens, France. |
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| Abstract: | OBJECTIVE: Calcium and vitamin D deficiency is common in older individuals, particularly those who live in nursing homes, and increases the risk of osteoporosis and fractures. METHODS: We conducted a randomized double-blind placebo-controlled study of combined supplementation with 500 mg of elemental calcium, as carbonate, and 400 IU of vitamin D bid for 12 months in women older than 65 years of age with vitamin D deficiency, defined as serum 25(OH)D concentrations
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