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Influence of haemodialysis on high-sensitivity C-reactive protein, lipoprotein(a), apolipoproteins A and B
Authors:Lippi Giuseppe  Tessitore Nicola  Salvagno Gian Luca  Bedogna Valeria  Bassi Antonella  Montagnana Martina  Lupo Antonio  Guidi Gian Cesare
Affiliation:Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico-Biomediche, Università degli Studi di Verona, Ospedale Policlinico G.B. Rossi, Piazzale Scuro, 10, 37121-Verona, Italy. ulippi@tin.it
Abstract:OBJECTIVES: There is debate on the influence of haemodialysis (HD) on lipoprotein(a). DESIGN AND METHODS: Lp(a), apo A, apo B and high-sensitivity C-reactive protein (hs-CRP) were measured in 46 patients pre- and post-HD. RESULTS: The median Lp(a) concentration significantly decreased post-HD (106 vs. 145 mg/L, p<0.001). No significant variations were observed for apo A, apo B and hs-CRP. Comparable results were observed with high- and low-flux membranes. CONCLUSION: HD is effective in lowering Lp(a).
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