| 脑血管病并发神经源性肺水肿炎症机制的探讨 |
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| 引用本文： | 王军,张均. 脑血管病并发神经源性肺水肿炎症机制的探讨[J]. 内科急危重症杂志, 2011, 17(6): 358-359 |
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| 作者姓名： | 王军 张均 |
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| 作者单位： | 南京大学医学院附属鼓楼医院 南京210013 |
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| 摘 要： | 目的：讨脑血管病（CVD）并发神经源性肺水肿（NPE）的炎症反应机制。方法：选择（CVD）患者65例和健康体检者24例;血清内皮素（ET-1）测定方法采用人ET-1酶免疫检测试剂盒;血清TNF-α测定采用双夹心ELISA法;血清超敏C反应蛋白（hsCRP）水平测定采用免疫比浊法。结果：（CVD）组ET-1、TNF-α、hsCRP水平均高于对照组（P〈0.05）;并发NPE的患者ET-1、TNF-α水平均高于无NPE的患者（P〈0.05）。结论：ET-1和TNF-α介导的炎症损伤机制在神经源性肺水肿中可能起重要作用。
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| 关 键 词： | 脑血管病 神经源性肺水肿 内皮素-1 肿瘤坏死因子A |
Nvestigation on the Inflammatory Mechanism of Cerebral Vascular Disease Complicated With Neurogenic Pul- monary Edema |
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| WANG Jun,ZHANG Jun. Nvestigation on the Inflammatory Mechanism of Cerebral Vascular Disease Complicated With Neurogenic Pul- monary Edema[J]. Journal of Internal Intensive Medicine, 2011, 17(6): 358-359 |
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| Authors: | WANG Jun ZHANG Jun |
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| Affiliation: | WANG Jun,ZHANG Jun. The Affiliated Drum Tower Hospital of Nanjing University Medical School,Nanjng 210013,China |
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| Abstract: | Objective: To explore the inflammatory mechanism of cerebral vascular disease ( CVD) complicated with neurogenic pulmonary edema ( NPE) . Methods: Sixty-five cases with CVD and 26 healthy volunteers were involved in the study. Endothelin-1 ( ET-1) was detected by the human TiterZyme Enzyme Immunometric Assay ( EIA) Kit,plasma level of tumor necrosis factor ( TNF-a) was measured by the method of ELISA and the serum level of high sensitivity C-reactive protein ( hsCRP) was measured with immune turbidimetry. R... |
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| Keywords: | Cerebral vascular disease Neurogenic pulmonary edema Endothelin-1 Tumor necrosis factor-α |
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