| 湖北省维持性血液透析患者丙型肝炎病毒感染调查 |
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| 引用本文： | 韩颖,熊薇. 湖北省维持性血液透析患者丙型肝炎病毒感染调查[J]. 内科急危重症杂志, 2011, 17(4): 208-209,222 |
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| 作者姓名： | 韩颖 熊薇 |
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| 作者单位： | 华中科技大学同济医学院附属同济医院,武汉,430030 |
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| 摘 要： | 目的：调查维持性血液透析患者丙型肝炎病毒（HCV）感染情况，并探讨其相关危险因素。方法；对湖北省84所医院3608例维持性血液透析（MHD）患者，采用ELISA法检测血清标志物HCV抗体。同时调查其输血史和透析史，进行相关性分析。结果：3608例MHD患者中，HCV感染率5．88％。有输血史HCV感染率（7．12％）显著高于无输血史者（2．13％，P〈0．01）。HCV阳转率透析时间小于1年为0．98％，透析1～2年为4．19％，透析2～3年为4．59％，透析3年以上为13．06％（P〈0．01）。且随着每周透析次数的增加，HCV的阳转率也明显上升（P〈0．05）。接受过1所医院透析的患者，HCV阳转率为3．09％，接受过2所为5．84％，接受过3所为7．44％，接受4所及以上为11．29％（P〈0．01）。结论：反复输血、透析时间长、透析次数多、接受多家医院透析是MHD患者感染HCV高的重要因素。减少输血、加强透析治疗环节院内感染的质量控制对预防HCV感染有重要意义。
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| 关 键 词： | 维持性血液透析 丙型肝炎病毒 |
Investigation on Hepatitis C Virus Infection in Patients With Maintenance Hemodialysis in Hubei Province |
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| HAN Ying,XIONG Wei. Investigation on Hepatitis C Virus Infection in Patients With Maintenance Hemodialysis in Hubei Province[J]. Journal of Internal Intensive Medicine, 2011, 17(4): 208-209,222 |
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| Authors: | HAN Ying XIONG Wei |
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| Affiliation: | HAN Ying,XIONG Wei.Tongji Hospital Affiliated to Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China |
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| Abstract: | Objective:To investigate hepatitis C virus(HCV) infection in patients with maintenance hemodialysis(MHD) and to explore its associated risk factors.Methods:Serum samples of 3 608 patients with MHD in 84 hospitals of Hubei Province were tested for anti-HCV antibodies by the method of ELISA.History of blood transfusion and hemodialysis were investigated and their correlation was analyzed.Results:The HCV infection rate was 5.88% among 3 608 patients with MHD.Infection rate(7.12%) was much higher in patients wi... |
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| Keywords: | Maintenance hemodialysis Hepatitis C virus |
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