| 酪酸梭菌活菌散治疗儿童腹泻的疗效及机制 |
| |
| 引用本文： | 夏丽红.酪酸梭菌活菌散治疗儿童腹泻的疗效及机制[J].中国生化药物杂志,2012,33(2):184-186. |
| |
| 作者姓名： | 夏丽红 |
| |
| 作者单位： | 华中科技大学同济医学院附属普爱医院儿科,湖北武汉,430033 |
| |
| 摘 要： | 目的探讨酪酸梭菌活菌散对儿童腹泻血浆血管活性肠肽(VIP)、神经肽Y(NPY)和肠黏膜5-羟色胺(5-HT)的影响。方法儿童腹泻患者125例。其中60例患者采用常规治疗,作为对照组,另外65例患者作为观察组,在常规治疗基础上,服用酪酸梭菌活菌散,500 mg/次,2～4次/d,治疗7 d,观察疗效和治疗前后血浆VIP、NPY和肠黏膜5-HT的变化。结果观察组有效率明显高于对照组(P<0.05);两组治疗后血浆VIP水平和肠黏膜5-HT的表达显著下降而NPY水平显著增加,与治疗前比较,差异显著(P<0.05);治疗后,观察组血浆VIP水平和肠黏膜5-HT的表达明显低于对照组(P<0.05),血浆NPY水平明显高于对照组(P<0.05)。结论酪酸梭菌活菌散可能通过降低血浆VIP和肠黏膜5-HT,增加血浆NPY,提高对腹泻的疗效。
|
| 关 键 词： | 酪酸梭菌活菌散 儿童腹泻 血管活性肠肽 神经肽Y 5-羟色胺 |
The clinical efficacy of Clostridium Butyricum Powder on children's diarrhea and its action mechanism |
| |
| XIA Li-hong.The clinical efficacy of Clostridium Butyricum Powder on children's diarrhea and its action mechanism[J].Chinese Journal of Biochemical Pharmaceutics,2012,33(2):184-186. |
| |
| Authors: | XIA Li-hong |
| |
| Institution: | XIA Li-hong(Puai Hospital Affiliated to Tongji Medical School of Huazhong University of Science and Technology,Wuhan 430033,China) |
| |
| Abstract: | |
| |
| Keywords: | |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
