The chondrogenic response to exercise in the proximal femur of normal and mdx mice |
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Authors: | David J Nye Jeffrey M Costas Jessica B Henley Jin-Kwang Kim Jeffrey H Plochocki |
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Affiliation: | (1) Arizona College of Osteopathic Medicine, Midwestern University, Glendale, AZ 85308, USA;(2) The Pennsylvania State University, University Park, PA 16802, USA |
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Abstract: | Background Submaximal exercise is used in the management of muscular dystrophy. The effects of mechanical stimulation on skeletal development are well understood, although its effects on cartilage growth have yet to be investigated in the dystrophic condition. The objective of this study was to investigate the chondrogenic response to voluntary exercise in dystrophin-deficient mice. |
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