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Nitrofurantoin transport by placental choriocarcinoma JAr cells: involvement of BCRP, OATP2B1 and other MDR transporters
Authors:Valeria Feinshtein  Gershon Holcberg  Alaa Amash  Noam Erez  Mazal Rubin  Eyal Sheiner  Hana Polachek  Zvi Ben-Zvi
Affiliation:(1) Department of Clinical Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel;(2) Division of Obstetrics and Gynecology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, 151, Beer Sheva, 84101, Israel;(3) The Shraga Segal Department of Microbiology and Immunology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel;
Abstract:

Objective  

To determine the role of BCRP in nitrofurantoin (NF) transport in JAr cells and the possible contribution of OATP2B1, P-gp and MRPs to this transport.
Keywords:
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