| EB病毒EBNA1/IgA与鼻咽癌分期的关系 |
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| 引用本文： | 成积儒,蔡永林,郑裕明,李军,莫永坤,钟青燕. EB病毒EBNA1/IgA与鼻咽癌分期的关系[J]. 华夏医学, 2009, 22(5): 829-831 |
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| 作者姓名： | 成积儒 蔡永林 郑裕明 李军 莫永坤 钟青燕 |
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| 作者单位： | 梧州市红十字会医院,广西梧州,543002;梧州市红十字会医院,广西梧州,543002;梧州市红十字会医院,广西梧州,543002;梧州市红十字会医院,广西梧州,543002;梧州市红十字会医院,广西梧州,543002;梧州市红十字会医院,广西梧州,543002 |
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| 摘 要： | 目的：探讨EB病毒EBNA1/IgA抗体与鼻咽癌临床分期的关系。方法：用酶联免疫吸附法（ELISA）检测211例未经治疗的鼻咽癌患者血清中EBNA1/IgA抗体,按＂92分期法＂进行分期,分别计算各T、N、M分期及临床分期的EBNA1/IgA抗体阳性率及抗体水平并进行统计学分析。结果：鼻咽癌患者的EBNA1/IgA抗体表达与性别和各年龄组没有相关性。EBNA1/IgA抗体rA值与原发灶T分期及颈淋巴结转移N分期差异均有统计学意义（P〈0.05） 与远处转移M分期差异无统计学意义（P〉0.05）。鼻咽癌早期（Ⅰ、Ⅱ期）患者的EBNA1/IgA抗体rA值显著低于晚期（Ⅲ、Ⅳ期）（P〈0.05）。结论：EBNA1/IgA抗体在早期鼻咽癌表达水平相对较低。对于评估鼻咽癌临床分期有一定的参考价值。
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| 关 键 词： | 鼻咽癌 EB病毒 EBNA1/IgA 临床分期 |
Relationship between Epstein-Barr virus EBNA1/IgA antibody and clinical stages of nasopharyngeal carcinoma |
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| CHENG Ji-yu,CAI Yong-lin,ZHENG Yu-ming,et al.. Relationship between Epstein-Barr virus EBNA1/IgA antibody and clinical stages of nasopharyngeal carcinoma[J]. Acta Medicinae Sinica, 2009, 22(5): 829-831 |
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| Authors: | CHENG Ji-yu CAI Yong-lin ZHENG Yu-ming et al. |
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| Affiliation: | CHENG Ji-yu,CAI Yong-lin,ZHENG Yu-ming,et al.Wuzhou Red Cross Hospital,Wuzhou 543002,China |
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| Abstract: | Objective:To evaluate the relationship between Epstein-Barr virus(EBV)EBNA1/IgA antibody and clinical stages of nasopharyngeal carcinoma(NPC).Methods: Serum samples derived from 211 untreated patients with NPC,who were categorized by the project of 92' stage,were examined for the presence of antibodies directed against EBNA1/IgA by using enzyme-linked immnunosorbent assay(ELISA).The positive rate and antibody level of EBNA1/IgA of different TNM stages and clinical stages were analyzed statistically.Results:... |
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| Keywords: | EBNA1/IgA |
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