| 麝鼠香对麻醉犬的心血管效应 |
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| 引用本文： | 陈玉山,金顺丹,董万超,佟煜人,华树芳,赵会英.麝鼠香对麻醉犬的心血管效应[J].中国中药杂志,1989,14(4):49-51. |
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| 作者姓名： | 陈玉山 金顺丹 董万超 佟煜人 华树芳 赵会英 |
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| 作者单位： | 中国农科院特产研究所 吉林市左家
(陈玉山，金顺丹，董万超，佟煜人，华树芳)，中国农科院特产研究所 吉林市左家(赵会英) |
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| 摘 要： | 实验结果表明,给麻醉犬静脉注射麝鼠香和天然麝香24mg/kg均能降低动脉血压,总外周阻力和心肌收缩力,但麝鼠香减慢心率的作用比麝香明显,并有降低心肌耗氧量的作用。此外,给小鼠腹腔注射麝鼠香和麝香120mg/kg,皆有显著地抗乏氧作用,但麝鼠香抗乏氧作用较弱。
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| 关 键 词： | 麝鼠香 天然麝香 心肌耗氧量 |
Effect of Muskrat on Cardiovascular System in Anesthetized Dogs |
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| Chen Yushan,Jin Shundan,Dong Wanchao,Tong Yuren,Hua. Shufang Zhao Huiying.Effect of Muskrat on Cardiovascular System in Anesthetized Dogs[J].China Journal of Chinese Materia Medica,1989,14(4):49-51. |
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| Authors: | Chen Yushan Jin Shundan Dong Wanchao Tong Yuren Hua Shufang Zhao Huiying |
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| Abstract: | Muskrat and musk are secretions from the fragrant glands of male adult musk-rat (Ondatra zibethica) and musk-deer respectively. In this paper, the pharmacological effects of muskrat and musk are studied. The result shows that a dose of 24mg/kg iv of muskrat or musk can decrease the HR, mAP, LVP, LVdp/dt max and TPR in anesthetized dogs. But muskrat has an effect of reducing MHO while musk has not. In addition, an injection of 120mg/kg of muskrat or musk endures hypoxia in mice. But this function of muskrat was weaker than that of musk. |
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| Keywords: | muskrat musk-rat musk |
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