| 维甲酸对体外培养成纤维细胞超微结构的影响 |
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| 引用本文： | 宋维铭,管正玉,孙广慈,郭唯,盛瑞红,王石麟. 维甲酸对体外培养成纤维细胞超微结构的影响[J]. 中华整形外科杂志, 1996, 0(1) |
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| 作者姓名： | 宋维铭 管正玉 孙广慈 郭唯 盛瑞红 王石麟 |
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| 作者单位： | 中国医学科学院整形外科医院，中日友好医院 |
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| 摘 要： | 为阐明维甲酸治疗瘢痕的作用机理，观察了维甲酸对体外培养成纤维细胞超微结构的影响，证明维甲酸对成纤维细胞合成胶原有抑制作用。提示维甲酸抑制胶原生成可能是治疗瘢痕作用机制的一个方面。
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| 关 键 词： | 维甲酸，成纤维细胞，超微结构，体外培养，瘢痕 |
The effects of retinoic acid on the ultrastructure of cultured fibroblasts. |
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| Song Weiming,Guan Zhengyu, Sun Guangci,. The effects of retinoic acid on the ultrastructure of cultured fibroblasts.[J]. Chinese journal of plastic surgery, 1996, 0(1) |
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| Authors: | Song Weiming Guan Zhengyu Sun Guangci |
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| Abstract: | The paper reports the effects of retinoic acid on the ultrastructure of cultured fibrob lasts. Electron microscopic observation (SEM and TEM) showed that fibrous substances on the cell sur face and outside the cell had decreased. The results indicated that retinoic acid inhibits collagen synthesis of fibroblasts. The possible mechanism of the effect of retinoic acid in the treatment of scar is discussed. |
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| Keywords: | Retinoic acid Ultrastructure Fibroblast Scar Culture in vitro |
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