急性脊髓损伤并应激性溃疡的高危因素分析

目的探讨急性脊髓损伤(ASCI)并应激性溃疡的发病因素及预防措施。方法162例ASCI患者,并发应激性溃疡21例,分析其发病的相关高危因素。结果ASCI合并应激性溃疡的发生率与脊髓损伤的部位、程度、低血压、代谢性酸中毒等差异有显著性(P<0·05),与患者是否手术、高热、有无预防性应用甲氰咪呱等差异无显著性(P>0·05)。结论对ASCI后应激性溃疡的预防,应重视原发脊髓损伤与继发性病理生理的早期处理。

Analysis of high risk elements related to stress ulcer following acute spinal cord injury

Objective To study pathogenic element and preventive methods on stress ulcer following acute spinal cord injury. Mathods 162 patients with acute spinal cord injury were studied, of which 21 were complicated with stress ulcer. The risk factors were studied. Results The incidence of stress ulcer following acute spinal cord injury was significantly increased in complete spinal cord injury, hypotension, metabolic acidosis and so on(P<0.05), while there was no effect with operation, hyperfever and cimetidine on prevention of stress ulcer following acute spinal cord injury(P>0.05). Conclusions The treatment of primary spinal cord injury and secondary pathophysiologic changes at early stage are very important in prevention of stress ulcer following acute spinal cord injury.