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婴幼儿哮喘患者血清RSV-IgE及尘螨特异性IgE检测
引用本文:陈胜寒,沈桂秀,余新平,刘孟秋,赵晓军,刘仲熊.婴幼儿哮喘患者血清RSV-IgE及尘螨特异性IgE检测[J].武汉大学学报(医学版),1997(2).
作者姓名:陈胜寒  沈桂秀  余新平  刘孟秋  赵晓军  刘仲熊
作者单位:Department of Pediatrics,First Affiliated Hosptal Hubei Medical University,Wuhan 430060,China
摘    要:检测38例婴幼儿哮喘患者、20例健康儿血清呼吸道合胞病毒特异性IgE(RSV-IgE)及尘螨特异性IgE。结果:RSV-IgE阳性率在哮喘患儿为47.4%,健康儿为5%(P<0.01);尘螨特异性IgE阳性率在哮喘患儿为26.3%,健康儿为5%(P<0.05)。提示在大多数婴幼儿中病毒感染诱发的哮喘占主要地位,而少部分患儿对尘螨过敏,须引起重视。因此,避免或控制尘螨及病毒感染,可减轻发作期症状,延长缓解期,将有助于防止发展成典型的儿童哮喘。

关 键 词:哮喘/病因学  呼吸道合胞病毒/免疫学  螨/免疫学  免疫球蛋白E类/血液

Detection of Respiratory Syncytial Virus specific IgE and Dust Mite specific IgE in Infant Asthma
Chen Shenghan,Shen Guixiu,Yu Xinping,et al.Detection of Respiratory Syncytial Virus specific IgE and Dust Mite specific IgE in Infant Asthma[J].Medical Journal of Wuhan University,1997(2).
Authors:Chen Shenghan  Shen Guixiu  Yu Xinping  
Abstract:We examined respiratory syncytial virus specific IgE (RSV IgE) and dust mite specific IgE in serum from 38 patients with infant asthma and 20 healthy children. The results showed that: RSV IgE antibody was present in 47.4 % of the patients or 5 % of the healthy children (P< 0.05 );Dust mite specific IgE was detected in 26.3 % of the patients or 5 % of the healthy children (P<0.05). It suggests that virus infection induces asthmatic attack in the majority of infants with asthma. But the minority of patients is allergic to dust mite. However, it is necessary to avoid dust mite allegen exposure and control virus infections. It will prevent the further development of asthma.
Keywords:asthma/ET  respiratory syncytial viruses/MI  mite/PS  immunoglobulin E/BL
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