2020年江西省1～69岁人群HBsAg、HBsAb流行率调查

目的 了解江西省1～69岁人群乙型病毒性肝炎(乙肝)(hepatitis B virus,HBV)血清流行状况。方法 采用分层多阶段整群随机抽样方法在江西省5个县(市、区)抽取5 119名对象,检测HBsAg、HBsAb,χ²检验分析HBsAg、HBsAb阳性率。结果 HBsAg、HBsAb总阳性率分别为8.05%、57.98%;HBsAg阳性率男性(9.29%)高于女性(7.22%)(χ²=7.10,P<0.01),农村(9.33%)高于城市(6.81%)(χ²=10.97,P<0.01),HBsAb阳性率男性(55.50%)低于女性(59.63%)(χ²=8.59,P<0.01),农村(55.92%)低于城市(59.95%)(χ²=2.69,P<0.05);HepB接种者、未接种者和接种史不详者HBsAg阳性率分别为3.43%、12.79%、9.54%(χ²=11.24,P<0.01),HBsAb阳性率分别为58.46%、...

Investigation on prevalence of HBsAg and HBsAb in population aged 1 to 69 years in Jiangxi Province in 2020

Objective To investigate the seroprevalence of hepatitis B virus (HBV) in people aged 1 to 69 years in Jiangxi Province. Methods A stratified multi-stage whole-group random sampling method was used to select 5 119 participants in five counties (cities and districts) of Jiangxi Province for the detection of HBsAg and HBsAb, and the positive rate of HBsAg and HBsAb was analyzed by chi-square test. Results The total positive rates of HBsAg and HBsAb were 8.05% and 57.98%, respectively. The positive rate of HBsAg was higher in men (9.29%) than in women (7.22%) (χ2=7.10, P<0.01) and higher in rural areas (9.33%) than in cities (6.81%) (χ2=10.97, P<0.01). The HBsAb positive rate was lower in males (55.50%) than in females (59.63%) (χ2=8.59, P<0.01) and lower in rural areas (55.92%) than in urban areas (59.95%) (χ2=2.69, P<0.05). For HepB vaccinators, unvaccinated population, and population with unknown vaccination history, the positive rate of HBsAg were 3.43%, 12.79%, and 9.54% (χ2=11.24, P<0.01), and the positive rates were 58.46%, 57.75%, and 57.33% for HBsAb (χ2=0.42, P>0.05). For age groups of 1 to 4, 5 to 16, 17 to 29, and 30 to 69 years old, the positive rates were 0.26%, 1.06%, 5.72%, and 11.79% for HBsAg (χ2=92.55, P<0.01) and 75.72%, 36.98%, 61.17%, and 60.03% for HBsAb, respectively (χ2=1.39, P<0.01). HBsAg positive rates in Donghu district, Shanggao county, Wuning county, Zhanggong district, and Longnan city were 5.05%, 6.93%, 8.44%, 8.30%, and 10.04%, respectively (χ2=2.78, P<0.01), and HBsAb positive rates were 62.32%, 55.20%, 52.81%, 61.43%, and 56.99% (χ2=23.13, P<0.01). Conclusion There were differences in gender, age and region in HBsAg and HBsAb positive rates in Jiangxi Province. The HBsAb positive rate is not high but HBsAg positive rate is very low in the immunization planning coverage population.