Vitamine D chez la personne âgée : pourquoi ? Quand ? Comment ? |
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| Institution: | 1. Département de gériatrie Bichat-Beaujon, secteur ambulatoire de Bretonneau, faculté de médecine Denis Diderot Paris 7 et EA 4466, faculté de pharmacie René Descartes Paris 5, hôpital Bichat, AP–HP, 46, rue Henri-Huchard, 75877 Paris cedex 18, France;2. Inserm UMR 1027, gérontopôle, hôpital universitaire de Toulouse, université de Toulouse III, 31059 Toulouse cedex 9, France;3. Inserm U845, service des explorations fonctionnelles, hôpital Necker-Enfants Malades, université René Descartes Paris 5, AP–HP, 75743 Paris cedex 15, France;1. Inra, UMR 1260, 13385 Marseille, France;2. Inserm, UMR 1062, « nutrition, obésité et risque thrombotique », 13385 Marseille, France;3. Faculté de médecine, Aix-Marseille université, 27, boulevard Jean-Moulin, 13385 Marseille cedex 05, France;1. Faculté de pharmacie de Limoges, 2 rue du Docteur-Marcland, 87025, Limoges cedex, France;2. Centre régional de pharmacovigilance, de pharmacoépidémiologie et d’information sur les médicaments, Service de pharmacologie, toxicologie et pharmacovigilance, CHU de Limoges, 2 avenue Martin-Luther-King, 87042, Limoges cedex, France;1. Service d’endocrinologie, Hôpital d’Instruction des Armées Bégin, Saint-Mandé, France;2. Service d’endocrinologie. Hôpital militaire d’Instruction Mohamed V, Rabat, Maroc |
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| Abstract: | Vitamin D deficiency is reported in young and older adults. However, elderly persons represent an important target for supplementation. First, aging of the skin reduces vitamin D synthesis. Second, lifestyle or dependency results in low sun exposure. More importantly, the effect of vitamin D deficiency may become more rapidly apparent in aging subjects with poorer bone and muscle reserve. Interventional studies that have shown positive clinical results of vitamin D supplementation have been conducted in aging subjects. Vitamin D supplementation reduces the risk of fracture and falls in the elderly, costs little, and this could have a major impact on public health. It is recommended to systematically supplement all elderly persons with vitamin D, with doses ranging from 800 to 1000 UI/day, either daily or 80,000 to 100,000 UI every 2–3 months. |
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| Keywords: | Vitamin D Elderly person Fracture Fall |
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