吸烟与代谢综合征的相关性调查与分析

目的探讨吸烟与代谢综合征的关系.方法应用整体抽样横断面调查方法,完成重庆地区3 717例自然人群问卷调查及口服75g葡萄糖耐量试验,检测空腹血糖、血脂、血浆胰岛素及糖负荷2h后血糖,测量空腹状态血压、腰围、体重、身高.结果 (1)887例正常人中,吸烟组体重指数(BMI)、腰臀比(WHR)、体重、腰围、甘油三酯(TG)及低密度脂蛋白胆固醇(LDL-C)高于非吸烟组,高密度脂蛋白胆固醇(HDL-C)低于非吸烟组.(2)3 379例资料完整自然人群按年龄分层后,40岁以下人群吸烟组糖尿病(DM)、糖耐量减低(IGT)、空腹血糖减损(IFG)、高血压、血脂紊乱、超重/肥胖及中心性肥胖的患病率高于非吸烟组.40～60岁年龄层吸烟组超重/肥胖及中心性肥胖、高TG、低HDL-C的患病率高于非吸烟组,60岁以上年龄层吸烟组代谢综合征患病率高于非吸烟组.结论吸烟与代谢综合征有关,是其发生、发展的重要环境因素之一.

An analysis and survey of correlation between cigarette smoking and metabolic syndrome

Objective To investigate the relationship between cigarette smoking and metabolic syndrome.Methods Questionaire and 75 gram oral glucose tolerance were conducted during a cross sectional study with clustering sampling in the citizens of Chongqing.Meanwhile glucose,lipid profile,insulin,body weight,body highth,waist circumference and blood pressure were measured.Results (1)Among 887 selected normal people,high density lipoprotein cholesterol(HDL C),body mass index(IBM),waist hip ratio(WHR),body weight,waist circumference,triglyceride(TG),low density lipoprotein cholesterol(LDL c) in smokers were higher than those in non smokers.(2)The occurrence was higher in smokers than that in non smokers inculding diabetes mellitus,impaired glucose tolerance(IGT),impaired fasting gulcose(IGF),hypertension,lipid disorder,overweight/obesity and central obseity under 40 years,the same as overweight/obesity,central obesity,high TG,low HDL C from 40 to 60 and metabolic syndrome over 60 with the age stratified among 3 379 citizens.Conclusion Cigarette smoking was one of the environmental factors which promoted the occurrence and development of metabolic syndrome.