| 克霉唑联合苦参凝胶治疗重度外阴及阴道假丝酵母菌病 |
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| 引用本文： | 陈炳锦,葛亚娟,朱芳,朱丽均,陈亚萍. 克霉唑联合苦参凝胶治疗重度外阴及阴道假丝酵母菌病[J]. 中国医药, 2008, 3(8): 500-501 |
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| 作者姓名： | 陈炳锦 葛亚娟 朱芳 朱丽均 陈亚萍 |
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| 作者单位： | 复旦大学附属上海市第五人民医院妇产科,上海,200240 |
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| 摘 要： | 目的探讨克霉唑联合苦参凝胶治疗重度外阴、阴道假丝酵母菌病的临床治疗效果和药物不良反应。方法98例外阴、阴道假丝酵母菌病患者采用随机单盲方法，分为克霉唑组34例、苦参凝胶组33例、克霉唑加苦参凝胶组31例，治疗后7d和月经后5d评估治疗效果。结果克霉唑组临床治愈率和真菌清除率稍高于苦参凝胶组，但无统计学意义（P〉0．05），克霉唑加苦参凝胶组在治疗后第7天和月经后第5天均明显优于其他2组（P〈0．05）。3组治疗耐受性好且均无严重药物不良反应发生。结论克霉唑与苦参凝胶联合应用显著提高治疗效果，在治疗过程中未见严重局部和全身的药物不良反应，值得临床推广。
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| 关 键 词： | 外阴 阴道假丝酵母菌病 苦参凝胶 克霉唑 |
Treatment of severe vulvovaginal candidiasis with clotrimazde combined with gelatin kushen |
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| CHEN Bing-jin,GE Ya-juan,ZHU Fang,ZHU Li-jun,CHEN Ya-ping. Treatment of severe vulvovaginal candidiasis with clotrimazde combined with gelatin kushen[J]. China Medicine, 2008, 3(8): 500-501 |
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| Authors: | CHEN Bing-jin GE Ya-juan ZHU Fang ZHU Li-jun CHEN Ya-ping |
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| Affiliation: | .( Department of Obstetrics ＆ Gynecology, Shanghai Fifth People＇ s Hospital of Fudan University , Shanghai 200240, China) |
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| Abstract: | Objective To evaluate the therapeutic effect and safety of gelatin Kushen in the treatment of severe vulvovaginal candidiasis.Methotis Ninty.eight patients of severe vulvovaginal candidiasis were treated randomly with clotrimazole,gelatin Kushen or elotrimazole combined with gelatin Kushen.The therapeutic effect and adverse reaction were observed at 7 days after treatment and 5 days after menstruation.Results The effective rates were similar between elotrimazole and gelatin Kushen(P＞0.05).Compared with single drug.the effective rate of clotrimazole combined with gelatin Kushen wal5 significantly increased(P＜0.05).No adverse reaction Was found.Conclusion Clotrimazole combined with gelatin Kushen was effective and safe in the treatment of severe v'ulvovaginal candidiasis. |
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| Keywords: | Vulvovaginal candidiasis Gelatin kushen: Clotrimzde |
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