| 新辅助化疗与乳腺癌病理组织形态学及分子水平相关基因的表达 |
| |
| 引用本文： | 刘巍,张祥宏. 新辅助化疗与乳腺癌病理组织形态学及分子水平相关基因的表达[J]. 中国肿瘤临床, 2005, 32(18): 1076-1080 |
| |
| 作者姓名： | 刘巍 张祥宏 |
| |
| 作者单位： | 河北医科大学基础研究所病理室,石家庄市,050017 |
| |
| 摘 要： | 新辅助化疗是指在实施手术或放疗之前应用的全身性化疗,对乳腺癌有良好的近期疗效,同时为化疗药体内药敏试验提供了可靠的依据.以往对新辅助化疗疗效的评定仅限于常规镜下观察化疗后病理形态学改变的组织学评定,结合肿瘤特异性标志物的检测是一种新尝试,从不同层面对新辅助化疗后乳腺癌组织的变化进行观察,客观评价新辅助化疗对指导临床个体化化疗的作用.
|
| 关 键 词： | 新辅助化疗 乳腺癌 基因 |
| 文章编号： | 1000-8179（2005）18-1076-05 |
| 收稿时间： | 2005-05-17 |
| 修稿时间： | 2005-05-172005-07-18 |
Neoadjuvant Chemotherapy and Pathological Histomorphology as well as Expression of Related Gene at Molecular Level in Breast Cancer |
| |
| Liu Wei,Zhang Xianghong. Neoadjuvant Chemotherapy and Pathological Histomorphology as well as Expression of Related Gene at Molecular Level in Breast Cancer[J]. Chinese Journal of Clinical Oncology, 2005, 32(18): 1076-1080 |
| |
| Authors: | Liu Wei Zhang Xianghong |
| |
| Affiliation: | ZengShu;ShenJiao |
| |
| Abstract: | Neoadjuvant chemotherapy is a systemic chemotherapy before surgical operation or radiotherapy. It is good for the breast cancer with the recent response rate and it offers the credible evidence to susceptibility test of chemotherapeutic agent in vivo. The evaluation on the response rate of neoadjuvant chemotherapy is only limited to the routine method of pathological histomorphology below the microscope. It is a new essay to analyze the relationship between the tumor markers and chemotherapy reaction, in order to observe the change of breast cancer tissues in different aspects after neoadjuvant chemotherapy with better prospect of clinical individual chemotherapy. |
| |
| Keywords: | Neoadjuvant chemotherapy Breast cancer Gene |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
