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水通道蛋白亚型AQP1-9在雄性小鼠生殖系统mRNA的表达
引用本文:赵丹,杜建时,杨柯,杨宝学,赵雪俭.水通道蛋白亚型AQP1-9在雄性小鼠生殖系统mRNA的表达[J].吉林大学学报(医学版),2004,30(1):52-55.
作者姓名:赵丹  杜建时  杨柯  杨宝学  赵雪俭
作者单位:1. 吉林大学基础医学院病理生理学教研室,吉林 长春130021;2. 吉林大学中日联谊医院血管外科,吉林 长春130031;3. 美国加利福尼亚大学旧金山医学院,美国 旧金山 CA94122
摘    要:目的:明确AQP1-9在雄性小鼠生殖系统的分布与表达。方法:应用RT-PCR技术检测AQP1-9在雄性小鼠生殖系统不同器官的表达。结果:在成年雄性小鼠的生殖系统中,有多种水通道的表达,睾丸中有AQP3、5、7、8、9表达;附睾头中有AQP3、6、8表达;附睾尾有AQP3、5、6、7、8表达;输精管中有AQP1、2、3、4、5、6、7的表达。结论:小鼠生殖系统中多种水通道蛋白的表达提示AQP与生殖功能有密切关系。

关 键 词:代谢  睾丸  代谢  附睾  代谢  输精管  代谢  疾病模型  动物    
文章编号:1671-587X(2004)01-0052-04
收稿时间:2003-03-20
修稿时间:2003年3月20日

AQP1-9 mRNA expression of water channel in reproductive tract of male mouse
ZHAO Dan ,DU Jian shi ,YANG Ke ,YANG Bao xue ,ZHAO Xue jian.AQP1-9 mRNA expression of water channel in reproductive tract of male mouse[J].Journal of Jilin University: Med Ed,2004,30(1):52-55.
Authors:ZHAO Dan  DU Jian shi  YANG Ke  YANG Bao xue  ZHAO Xue jian
Institution:1. Department of Pathophysiology,School of Basic Medical Sciences,Jilin University,Changchun130021,China;2. Department of Vascular Surgery,China-Japan Union Hospital,Jilin University,Changchun130031,China;3. San Francisco Meclical College of California University,San Francisso CA94122,USA)
Abstract:Objective\ To determine the expression and distribution of aquaporin 1-9(AQP1-9)in male reproductive tract of mouse. Methods The expressions of AQP1-9 in various organs of male reproductive tract of mouse was determined using RT PCR. Results The expression of AQP3,5,7,8,9 were present in mouse testis. AQP3,6,8 expression were found in capita epididymis and AQP3,5,6,7,8 in caudae epididymis. In vas deferens, the AQPs except for AQP8,9 were detected. Conclusions The different localization of AQP1-9 expression in male reproductive system of mouse shows that they may play an important role in physiological function of male reproductive system,especially for the maturation of sperm in different segments of male reproductive tract of mouse.
Keywords:aquaporins/metabolism  tesis/metabolism  epididymis/metabolism  vas deferens/metabolism  disease models  animal
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