| 虎金丸对CCl4所致实验性肝损伤的保护作用 |
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| 引用本文： | 黄兆胜,黎俏梅,王宗伟,刘明平,荣向路. 虎金丸对CCl4所致实验性肝损伤的保护作用[J]. 中国实验方剂学杂志, 1999, 5(2): 21-23 |
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| 作者姓名： | 黄兆胜 黎俏梅 王宗伟 刘明平 荣向路 |
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| 作者单位： | College of Chinese Material Medical，Guangzhou University of TCM，Guangzhou，510407 |
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| 摘 要： | 虎金丸ｉｇ小鼠，能显著降低ＣＣｌ４所致血中ＡＬＴ、ＡＳＴ、ＧＳＴ和肝中ＭＤＡ水平的升高；虎金丸ｉｇ大鼠制得药物血清后，以１０％浓度加入原代培养大鼠肝细胞培养液中，能显著降低１０ｍｍｏｌ／ＬＣＣｌ４所致培养液中ＡＬＴ和ＭＤＡ的升高，并使细胞存活率由５５．９０％提高至８２．４５％。
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| 关 键 词： | 虎金丸 CCl_4致毒 小鼠肝脏 大鼠肝细胞 |
| 收稿时间： | 1998-03-31 |
Protective Effect of Hujin Pills on CCl4-induced Experimental Liver Injury |
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| Huang Zhaosheng,Li Qiaomei,Wang Zongwei,Liu Mingping,Rong Xianglu. Protective Effect of Hujin Pills on CCl4-induced Experimental Liver Injury[J]. China Journal of Experimental Traditional Medical Formulae, 1999, 5(2): 21-23 |
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| Authors: | Huang Zhaosheng Li Qiaomei Wang Zongwei Liu Mingping Rong Xianglu |
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| Affiliation: | College of Chinese Material Medical,Guangzhou University of TCM,Guangzhou,510407 |
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| Abstract: | After the mice were dosed with Hujin Pill for 6 days,the raised level of ALT,AST,GST in serum and MDA in liver caused by CCl 4 was ameliorated evidently.In addition,for primay cultured rat hepatocytes,rat serum containing Hujin Pills could remarkably decrease the raised level of ALT and MDA in the culture caused by 10 mmol/L CCl 4,and the cell viability was improved from 55 90% to 82 45%. |
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| Keywords: | hujin pills CCl 4 intoxicate mouse liver rat hepatocytes |
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