Complete genomic characterization of cell culture adapted human G12P[6] rotaviruses isolated from South Korea |
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| Authors: | Van Thai Than Van Phan Le Inseok Lim Wonyong Kim |
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| Affiliation: | (1) Department of Microbiology and Research Institute for Translational System Biomics, Chung-Ang University College of Medicine, Seoul, South Korea;(2) Department of Pediatrics, Chung-Ang University College of Medicine, Seoul, South Korea; |
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| Abstract: | Two unusual human rotavirus G12 strains, CAU195 and CAU214, were isolated from female pediatric diarrhea patients under 12 months of age in 2006 using a cell culture system and their full genome sequences were analyzed. The 11 gene segments of both Korean G12 strains were classified as G12-P[6]-R1-C1-M1-I1-A1-N1-T1-E1-H1 genotypes. Notably, the Korean strains were of the same genotypes as previously reported strains isolated from Bangladesh in 2003 (Dhaka12-03), from the United States in 2005–2006 (US6597), and from Germany in 2008 (GER126-08 and GER172-08), suggesting that closely related G12P[6] strains are persistent and widespread. |
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