多软膜下横切术对外伤性功能区顽固性癫痫的治疗

目的 探讨癫痫病灶切除辅以多处软膜下横切术(MST)对外伤性癫痫治疗的临床效果。方法 32例外伤性癫痫中，癫痫病灶切除加MST28例，癫痫病灶切除加MST和胼胝体前2／3潜行切开术4例；术后12～36个月随访观察。结果 术后早期可见6例一过性肢体肌力减弱，11例一过性火语，均在5～10d内恢复：32例手术出院后12～36个月随访，完全无发作13例，发作次数减少75％以上10例，发作次数减少51％～75％6例，3例效差或无改善。结论 癫痫病灶切除加MST是治疗外伤性癫痫安全且有效的方法。

Epileptogenic lesionectomy combined with multiple subpial transection for the treatment of posttraumatic intractable epilepsy

Objective To investigate the clinical effects of epileptogenic lesionectomy combined with multiple subpial transection (MST) for the treatment of post-traumatic epilepsy (PTE). Methods In 32 cases with PTE treated in our hospital from 2000 to 2004,28 cases accepted epileptogenic lesionectomy combined with MST,and the other 4 cases added with anterior 2/3 corpus callosotomy. All were followed up 12~36 months after the surgery. Results 6 cases showed a transient decreased limb muscle power and 11 cases had transient aphasia in early period after operation,but all recovered in 5~10 d later. Seizure disappeared totally in 13 cases (40.6%); the frequency decreased significantly (>75%) in 10 cases (31.2%),51%~75% in 6 cases (18.7%); poor effect or no improvement occurred in 3 cases. The total effective rate was 90.5%. Conclusion The epileptogenic lesion resection combined with MST is an effective and safe surgical technique in the treatment for PTE.