Adrenal ganglioneuroma: report of a new case |
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Authors: | Cihangir Erem Ozge Ucuncu Irfan Nuhoglu Akif Cinel Umit Cobanoglu Adem Demirel Ekrem Koc Mustafa Kocak and Gulname Fndk Guvendi |
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Institution: | (1) Department of Internal Medicine, Karadeniz Technical University, Trabzon, Turkey;(2) Department of General Surgery, Karadeniz Technical University, Trabzon, Turkey;(3) Department of Patology, Karadeniz Technical University, Trabzon, Turkey;(4) K.T.ü. Tıp Fakültesi, İ? Hastalıkları Anabilim Dalı, Endokrinoloji ve Metabolizma Hastalıkları Bilim Dalı, 61080 Trabzon, Turkey |
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Abstract: | Although adrenal ganglioneuroma (GN) is a rare tumor originating from the neural crest tissue of the sympathetic nervous system,
detection of this tumor has increased, as imaging procedures such as ultrasonography (US) and computed tomography (CT) have
become prevalent. The clinical presentation for most patients is asymptomatic, and most of those tumors are hormone silent.
We describe a case of adrenal GN incidentally diagnosed in a 68-year-old female patient. Physical examination, routine laboratory
studies, and hormonal tests were within normal ranges. Abdominal CT and magnetic resonance imaging showed a solid oval tumor
approximately 6 × 4 cm in the left adrenal gland without remarkable signs of malignancy. Left adrenalectomy was performed
for treatment purposes. Histological diagnosis of the tumor was a ganglioneuroma originating from the adrenal medulla. Adrenal
GN occurs rarely in adults and preoperative diagnosis is difficult, especially in asymptomatic cases. It needs careful evaluation
and surgical treatment. According to our knowledge, this is the fifth case of adrenal GN in an adult patient from Turkey in
English literature. |
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Keywords: | Adrenal gland Ganglioneuroma Incidentaloma |
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