神经内镜辅助下颅面联合入路切除前颅底沟通性肿瘤19例

目的 总结在神经内镜辅助下前颅底沟通性肿瘤的手术切除与修复方法.方法 对19例前颅底沟通性肿瘤采用神经内镜辅助下颅面联合入路进行鼻腔、鼻窦-颅沟通性肿瘤(15例)、鼻-眶-颅沟通性肿瘤(4例)切除术,并同期行带蒂额肌帽状腱膜裂层颅骨瓣修复术.结果 19例患者术后均未发生脑脊液漏和颅内感染,肿瘤全切率78.9%,次全切除率15.8%,部分切除率5.3%.良性肿瘤4例,至今全部存活;恶性肿瘤15例,2年生存11例,3年生存8例,5年以上生存6例.结论 神经内镜辅助下颅面联合入路,进行前颅底沟通性肿瘤切除术,加以带蒂额肌帽状腱膜裂层颅骨瓣修复,切除范围安全彻底,修复方便可靠,是一种较为理想的手术切除及修复方法.

The neuroendoscope-assisted surgical treatment of communicating tumors on anterior skull base:report of 19 cases

Objective To investigate the clinical effects of communicating tumors on anterior skull base with neuroendoscope-assisted surgery. Methods Nineteen eases of crani-nosel and crani-orbital nosel communicating tumors underwent the combined craniofacial approach. The defect of anterior skull base was repaired with the compound flap with pedicel frontal galea muscle and temporalis myofascial flap.Results All 19 patients were successfully treated without CSF leak and cranial infection. The tumor total re-section rate was 78.9%, subtotal resection rate was 15.8% ,partial resection rate was 5.3%. Four patients of benign tumor were survival,15 patients of malignant tumor 2- year survival was 11, 3-year survival was 8,above 5- year survival was 6. Conclusion The neuroendoscope-assisted combined craniofacial approach can provide a relatively safe and effective resection for communicating tumors on anterior skull base,and has better clinicall value.