苯巴比妥早期干预早产儿黄疸66例

目的观察苯巴比妥治疗早产儿黄疸的疗效。方法对照组给予光疗和茵枙黄注射液治疗,治疗组在对照组治疗的基础上给予苯巴比妥5 mg.kg-1.d-1,分3次口服,疗程7 d。结果治疗组总有效率明显高于对照组(P<0.01);治疗组经皮胆红素值和高胆红素血症发生率明显低于对照组(P<0.05,P<0.01)。结论苯巴比妥治疗早产儿黄疸疗效好,可以降低患儿血胆红素浓度,降低早产儿高胆红素血症的发生率。

Early intervention effect of phenobarbital in sixty-six preterm infants with jaundice

Objective To observer the effect of phenobarbital in preterm infant with jaundice.Methods Phototherapy and yinzhihuang injection were used in control group,based on the control group,5 mg·kg-1·d-1 phenobarbital was used in treatment group,three times a day for seven days as a course of treatment.Results The total effective rate of treatment group was obviously higher than those of control group(P<0.01),and the value of per cutem bilirubin and incidence of hyperbilirubinemia were significantly lower than those of control group.(P<0.05,P<0.01).Conclusion Curative effect of phenobarbital in preterm infant with jaundice is good.It can reduce the patient's concentration of hemobilirubin and the incidence of hyperbilirubinemia in preterm infant.