台州市HIV感染者高血压治疗率与控制率现状

目的 了解台州市人类免疫缺陷病毒（human immunodeficiency virus，HIV）感染者高血压治疗与控制现状，为针对性开展高血压控制工作提供依据。 方法 基于2017年“HIV与衰老相关疾病前瞻性队列研究”的基线数据，于2019年9―12月对到台州市各区县疾病预防控制中心符合基线高血压标准的242名HIV感染者进行问卷调查和体格检查。 结果 本次调查时，HIV感染者的高血压治疗率和控制率分别为44.2%和54.5%。年龄≥45岁、有高血压家族史以及合并高血脂的病人高血压治疗率较高（均有P < 0.05）；未接受治疗者高血压控制率高于采用药物治疗者（χ²=12.067，P < 0.001）；接受治疗者高血压控制率影响因素为有高血压家族史（aOR=0.153，95% CI：0.055~0.420）、基线调查时为轻度（aOR=0.130，95% CI：0.041~0.406）或中重度高血压（aOR=0.263，95% CI：0.075~0.915）；未接受治疗者高血压控制率影响因素为抗病毒治疗时间≥6年（aOR=0.355，95% CI：0.165~0.765）；单一用药与联合用药者高血压控制率差异无统计学意义。 结论 HIV感染者的高血压治疗率和控制率有待提高。应加强该人群血压监测和管理工作，并进一步研究HIV感染合并高血压者的治疗方案。

Hypertension treatment and control rates among HIV-infected individuals in Taizhou City

  Objective   To investigate the treatment and control rates of hypertension among HIV-infected individuals in Taizhou City and provide evidences for prevention and control of hypertension.   Methods   Data was assessed from baseline survey of Comparative HIV and Aging Research in Taizhou (CHART) in 2017 and HIV-infected individuals who met diagnostic standard of hypertension at baseline were surveyed when they came to local Centers for Disease Control and Prevention to receive regular follow-up medical care and assessment, between September and December 2019. Questionnaire interview and physical examination were carried out.   Results   Rates of hypertension treatment and control were 44.2% and 54.5%, respectively. The rate of hypertension treatment were significantly higher among those aged over 45 years, with family history of hypertension and hyperlipemia (all P < 0.05). The rate of hypertension control was significantly lower among those on antihypertensive therapy than those without antihypertensive therapy (χ2=12.067, P < 0.001). Among those on antihypertensive therapy, family history of hypertension (aOR=0.153, 95% CI:0.055-0.420) and have been diagnosed with mild (aOR=0.130, 95% CI:0.041-0.406) or moderate and severe hypertension (aOR=0.263, 95% CI:0.075-0.915) at baseline were significantly associated with rate of hypertension control, whereas among those without antihypertensive therapy, only the time of antiviral treatment ≥ 6 years (aOR=0.355, 95% CI:0.165-0.765) was significantly associated with rate of hypertension control. No significance difference in hypertension control was found between those using single treatment drug and those using combined treatment drugs.   Conclusions   The hypertension treatment and control rates among HIV-infected individuals in Taizhou City remain to be improved. There is an urgent need for blood pressure screening and treatment management among HIV-infected individuals. Further research is needed to develop the effective hypertension treatment strategies for this population.