新疆伊犁州35~74岁人群膳食炎症指数与超重/肥胖的关系

目的  分析膳食炎症指数(dietary inflammatory index，DⅡ)与超重/肥胖之间的关联，为研究肥胖的炎症机制提供科学依据。 方法  2019年1月―5月在新疆伊犁州霍城县招募35~74岁队列成员并完成基线调查，采用统一制定的调查问卷，收集研究对象一般人口特征、行为方式等信息。采用食物频率调查表(food frequency questionnaires，FFQ)，调查研究对象膳食摄入情况，计算DⅡ，评估膳食的炎症潜能。 结果  研究对象2 241人，超重的检出率为38.51%，肥胖的检出率为32.04%；总研究对象DⅡ评分以正值为主，总体膳食属于促炎性膳食；调整年龄、民族、性别、文化程度、家庭收入后，Log-binomial回归分析模型结果显示DⅡ与超重及肥胖存在相关性，最大促炎组患超重及肥胖的风险是最大抗炎组的1.32倍(PR=1.32，95% CI：1.10~1.57，P=0.015)，其中DⅡ与超重仅在Q1(最大抗炎)与Q4(最大促炎)组间发现相关性(PR=1.26，95% CI：1.09~1.47，P=0.002)，DⅡ与肥胖在每组均存在相关性，随着DⅡ评分的增加，研究对象患肥胖的风险增加。 结论  膳食炎症指数与超重/肥胖之间存在相关性，膳食的肥胖效应可以从炎症的角度进行深入分析。

Relationship between dietary inflammatory index and overweight/obesity in people aged 35 - 74 years in Yili Prefecture,Xinjiang

  Objective  To analyze the association between dietary inflammation index (DⅡ) and overweight/obesity, and to provide scientific basis for studying the inflammatory mechanism of obesity.  Methods  From January to May 2019, the subjects were all adults aged 35-74 years old in the baseline participating in the Xinjiang multi-ethnic natural population cohort construction and health follow-up study. The general demographic characteristics and behavior patterns of the subjects were collected by using an unified questionnaire. The DⅡ score was calculated from a diet intake assessed by 127 food frequency questionnaires (FFQ).  Results  Among the 2 241 participants, the detection rate of overweight and obesity was 38.51% and 32.04%. Log-binomial regression analyses were used to estimate the prevalence ratios (PRs) and 95% confidence intervals (95% CIs) of DⅡ in relation to overweight/obesity. After adjusting for potential confounders, compared with the 1st quintile group, subjects from the 4th quintile group had a higher risk of overweight/obesity (PR = 1.32, 95% CI: 1.10-1.57, P=0.015). The association between DⅡ and overweight was only found between the 1st quintile group and the 4th quintile group (PR=1.26, 95% CI:1.09-1.47, P=0.002), but compared with the 1st quintile group, subjects from other groups all had higher risk of obesity.  Conclusions  There was a correlation between the dietary inflammatory index and overweight/obesity, the obesity effect of diet could be analyzed from the perspective of inflammation.