| 中国10个地区成年人自评健康状况与全因死亡、心血管疾病死亡风险的关联研究 |
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| 引用本文： | 董文红,吴晶,余灿清,宋兴月,吕筠,郭彧,卞铮,杨玲,陈怡平,陈铮鸣,潘安,李立明. 中国10个地区成年人自评健康状况与全因死亡、心血管疾病死亡风险的关联研究[J]. 中华流行病学杂志, 2021, 42(5): 763-770 |
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| 作者姓名： | 董文红 吴晶 余灿清 宋兴月 吕筠 郭彧 卞铮 杨玲 陈怡平 陈铮鸣 潘安 李立明 |
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| 作者单位： | 华中科技大学同济医学院公共卫生学院流行病与卫生统计学系/环境与健康教育部重点实验室, 武汉 430030;北京大学公共卫生学院流行病与卫生统计学系/北京大学公众健康与重大疫情防控战略研究中心/北京大学分子心血管学教育部重点实验室 100191;中国医学科学院, 北京 100730;英国牛津大学临床与流行病学研究中心纳菲尔德人群健康系/英国牛津大学医学研究委员会人口健康研究组 OX3 7LF |
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| 基金项目： | 国家重点研发计划精准医学研究重点项目（2017YFC0907504，2016YFC0900500，2016YFC0900501，2016YFC0900504）；中国香港KadoorieCharitable基金 |
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| 摘 要： | 目的:分析自评健康状况（SRH）与全因死亡和心血管疾病（CVD）死亡风险的关联性。方法:研究对象来自中国慢性病前瞻性研究，剔除有逻辑错误和信息缺失的个体，最终纳入512 713名研究对象。SRH在基线问卷调查时搜集，包括整体自评健康状况（GSRH）及与同龄人相比自评健康状况（ASRH）；死亡事件及原因通过链接到疾病死亡...
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| 关 键 词： | 自评健康状况 心血管疾病 死亡 队列研究 |
| 收稿时间： | 2020-06-22 |
Self-rated health measures and their relations to all-cause and cardiovascular mortality in adults from 10 regions of China |
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| Dong Wenhong,Wu Jing,Yu Canqing,Song Xingyue,Lyu Jun,Guo Yu,Bian Zheng,Yang Ling,Chen Yiping,Chen Zhengming,Pan An,Li Liming. Self-rated health measures and their relations to all-cause and cardiovascular mortality in adults from 10 regions of China[J]. Chinese Journal of Epidemiology, 2021, 42(5): 763-770 |
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| Authors: | Dong Wenhong Wu Jing Yu Canqing Song Xingyue Lyu Jun Guo Yu Bian Zheng Yang Ling Chen Yiping Chen Zhengming Pan An Li Liming |
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| Affiliation: | Department of Epidemiology and Biostatistics, and Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China;Department of Epidemiology and Biostatistics, School of Public Health, Peking University/Peking University Center for Public Health and Epidemic Preparedness & Response/Peking University Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing 100191, China;Chinese Academy of Medical Sciences, Beijing 100730, China;Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health/Medical Research Council Population Health Research Unit, University of Oxford, Oxford OX3 7LF, UK |
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| Abstract: | Objective To examine the association between self-rated health status (SRH) and all-cause and cardiovascular mortality. Methods A total of 512 713 adults aged 30-79 years from 10 areas of China were followed from baseline (2004-2008) until 31 December 2016 in the China Kadoorie Biobank study. Global and age-comparative SRH[general self-rated health status (GSRH) and age-comparative self-rated health status (ASRH), respectively] were asked in baseline questionnaires. Causes for mortality were monitored through linkage with established Disease Surveillance Point system and health insurance records. Multivariable Cox proportional regression models were used to estimate the HRs and 95%CIs for the association between SRH measures and all-cause or cardiovascular mortality. Results During an average of 9.9 years'' follow-up, 44 065 deaths were recorded, among which 17 648 were from cardiovascular disease. Compared with excellent GSRH, the HR(95%CI) for all-cause and cardiovascular mortality associated with poor GSRH was 1.84(1.78-1.91) and 1.94(1.82-2.06), respectively. Relative to better ASRH, the HR(95%CI) for all-cause and cardiovascular mortality associated with worse ASRH was 1.75(1.70-1.81) and 1.83(1.73-1.92), respectively. Conclusion In this large prospective cohort study in China, participants reporting poor GSRH or worse ASRH had significantly higher risk of all-cause and cardiovascular mortality. |
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| Keywords: | Self-rated health status Cardiovascular disease Mortality Cohort study |
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